ISSN : 1738-4125(Print)
ISSN : 2287-7509(Online)
ISSN : 2287-7509(Online)
페놀 노출 근로자의 요중 페놀농도에 영향을 미치는 요인
The factors that influenced urinary phenol in workers exposed to phenol
Abstract
Objectives : The purpose of this study is to identify the characteristics that affect the urinary phenol ofworkers exposed to phenol.
Subjects and Methods : Total 41 workers were selected at bisphenol A manufacturing plant and their urinaryphenol concentration were measured before and after work along with the phenol concentration in theworkplace air, and carried out a survey on work characteristics and lifestyle factors that could affect urinaryphenol.
Results : The phenol concentration in air during work hours was 0.91 (non-detection~2.88) mg/m3, and theworker’s urinary phenol concentrations before and after work were 100.27±75.76 and 138.13±109. 58mg/g creatinine, respectively, which showed a statistically significant increase. Comparing smoking andurinary phenol concentration, smokers had 194.54±137.52 mg/g creatinine while non-smokers had108.88±80.10 mg/g creatinine, thus showing the urinary phenol concentration of smokers to be statisticallysignificantly higher (p=0.046). The urinary phenol concentration increased as work hours, the frequency ofskin exposure to phenol, and the amount of drinking increased, and there were differences in itsconcentration depending on the work type and whether or not workers wore protective gear.The results of carrying out a multiple regression analysis showed that phenol concentration in air, workhours, frequency of skin exposure, and smoking were statistically significant. In other words, the urinalphenol concentration increased more for smokers than for non-smokers, when work hours became longer,and when the frequency of skin exposure was over five times.
Conclusions : The factors that influenced urinary phenol in workers exposed to phenol were phenolconcentration in air, work hour, frequency of skin exposure, smoking, work and lifestyle habits. Accordingly,biological monitoring for phenol exposure assessment must reflect these factors, and effort must be madeto reduce skin exposure at workplace.
Subjects and Methods : Total 41 workers were selected at bisphenol A manufacturing plant and their urinaryphenol concentration were measured before and after work along with the phenol concentration in theworkplace air, and carried out a survey on work characteristics and lifestyle factors that could affect urinaryphenol.
Results : The phenol concentration in air during work hours was 0.91 (non-detection~2.88) mg/m3, and theworker’s urinary phenol concentrations before and after work were 100.27±75.76 and 138.13±109. 58mg/g creatinine, respectively, which showed a statistically significant increase. Comparing smoking andurinary phenol concentration, smokers had 194.54±137.52 mg/g creatinine while non-smokers had108.88±80.10 mg/g creatinine, thus showing the urinary phenol concentration of smokers to be statisticallysignificantly higher (p=0.046). The urinary phenol concentration increased as work hours, the frequency ofskin exposure to phenol, and the amount of drinking increased, and there were differences in itsconcentration depending on the work type and whether or not workers wore protective gear.The results of carrying out a multiple regression analysis showed that phenol concentration in air, workhours, frequency of skin exposure, and smoking were statistically significant. In other words, the urinalphenol concentration increased more for smokers than for non-smokers, when work hours became longer,and when the frequency of skin exposure was over five times.
Conclusions : The factors that influenced urinary phenol in workers exposed to phenol were phenolconcentration in air, work hour, frequency of skin exposure, smoking, work and lifestyle habits. Accordingly,biological monitoring for phenol exposure assessment must reflect these factors, and effort must be madeto reduce skin exposure at workplace.
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