ISSN : 1738-4125(Print)
ISSN : 2287-7509(Online)
ISSN : 2287-7509(Online)
조혈모세포이식 대상 환자를 위한 이동식 고성능 공기여과장치의 성능
Development of a Mobile HEPA Filter Unit and Assessment of Its Function for Patients Receiving Hemopoietic Stem Cell Transplantation
Received 20 July 2005, accepted 27 January 2006
Abstract
We have invented mobile HEPA filter unit of hemopoietic stem cell transplantation clean room (class 100),which is a capsule type to protect the patient from being infected by harmful Aspergillus spore. Thisequipment is based on the basic structure of US Federal Standard 209D, biological clean room standard ofNASA NHB 5340-2 and measurement standard of Japanese JACA No. 24-1989. Performance of HEPA filterwas evaluated by dioctyl phthalate (DOP) test method, resulting in 99.97% efficiency for 0.3 ㎛ particles.HEPA filter unit used only 98 W electricity with 24 V storage cell for the patient's treatment for over threehours. When the wind speed was 0.2 to 0.3 m/sec as in bone marrow transplantation clean room, the air flowwas constant laminar vertical type. When the amount of dust was measured in the hospital, the equipmentmaintained the grade of clean class 100 and microbe was not detected. The noise level was less than 52dB(A). The amounts of microbe inside and outside the building were almost same. The amount was evenmore in cancer sick room, serious case room and X-rays room than in the general rooms. Also, elevators andstair room were found to transport dust to other areas. Even though the patient with low immunity can beprotected from Aspergillus spore by a HEPA filter unit, the system preventing microbe system such as BMTclean room should be placed in rooms such as PET, CT, MRI, and radiation room so that the patients canbe protected from having infected by the extremely harmful Aspergillus spore.
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