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ISSN : 1738-4125(Print)
ISSN : 2287-7509(Online)
Journal of Odor and Indoor Environment Vol.7 No.1 pp.17-24
DOI :

방사선조사 시 Squalene이 mice 혈청에 미치는 효과

오병준1), 동경래1,2)*, 박용순1), 권대철3), 정재은4,5), 구은회6,7)
1)광주보건대학 방사선과, 2)조선대학교 원자력공학과, 3)신흥대학 방사선과
4)남부대학교 디지털경영정보학과, 5)삼육의료원 의공학실, 6)서울대학교 영상의학과
7)순천향대학교 물리학과

Comparative Analysis on the Effects Squalene on Mice Serum when Irradiation

Kyung Rae Dong1,2)*, Byung Joon Oh1), Yong Soon Park1), Dae Cheol Kweon3), Jae Eun Jung4,5), Eun Hoe Goo6,7)
1)Department of Radiological Technology, Gwangju Health College University
2)Department of Nuclear Engineering, Chosun University
3)Department of Radiologic Science, Shin Heung College University of Radiological Technology, Shinheung College University
4)Department of Digital Management and Information, Nambu University
5)Department of Biomedical Engineering, Sahmyook Medical Center
6)Department of Radiology, Seoul National University Hospital
7)Department of Physics, Soonchunhyang University

Abstract

When radiation is irradiated onto biological tissue, the occurrence of biological change has been alreadydemonstrated and the change of blood composition and chromosome abnormality could be suggested as therepresentative biological markers which can identify the disturbance caused by radiation exposure. Recently,radiation treatment is performed for the treatment of cancer. Since the protection of blood within normaltissue is very important, the development of radioprotective has been made continuously to protect normaltissues. Squalene is a very important precursor in the biosynthesis of cholesterol. It is the hydrocarboncontained in the liver of deep sea sharks and in olive oils, and large quantity of it is contained in skin,abdominal fat tissue, subcutaneous fat tissue, lymphatic gland, pancreas and in heart muscle. Because of 6double bonds in SQ, it could easily bind with oxygen ions to have the hazardous oxygen removal capacityalong with the effects of scar treatment, blood vessel expansion, inhibitory action of arteriosclerosis, and hasbeen reported to have the effects on myocardial infarction and liver disease, treatment for burn. It has beenreported to have active effect of fibroblast. Therefore, the current study was conducted to know the changeof total protein, albumin, total cholesterol and glucose in serum after the injection of whole body radiationof SQ in mouse.
Irradiation,biological change,Radioprotective,Squalene
A9RCA27.pdf334.8KB

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