ISSN : 2288-9167(Print)
ISSN : 2288-923X(Online)
대사증후군 구성요소와 유기용제 노출과의 관계
김상욱1,2, 원종욱2,3,4, 지선하2, 김치년2,3, 박용성5, 정우진2,3,4,, 노재훈2,3,4,*
1(재)한국의학연구소 여의도센터
2연세대학교 보건대학원
3연세대학교 산업보건연구소
4연세대학교 의과대학 예방의학교실
5강동 경희대학교 병원
Relationship between the components of metabolic syndrome and the organic solvent exposure
Jaehoon Roh
2,3,4,*, Sang Wook Kim
1,2, Jong Uk Won
2,3,4, Sun Ha Jee
2, Chi Nyon Kim
2,3, Yong Sung Park
5,
Woo Jin Jung
2,3,4
2Graduate School of Public Health, Yonsei University
3Institute for Occupational Health, Yonsei University
4Department of Preventive Medicine, Yonsei University
1Korea Medical Institute Yeouido center
5Hospital at Gang-dong, Kyung Hee University
(Received 29 November, 2013, Revised 27 February, 2014, Accepted 12 March, 2014)
Abstract
The purpose of this study is to detect metabolic syndrome components related to exposure of organic solventthrough comparison and analysis of metabolic syndrome components between workers at the workplace exposedto organic solvent (toluene, xylene, styrene) and workers at general workplace. During the period from Januaryto December 2010, the survey was conducted against male workers of 168,769 persons with age group 30-59completed medical checkup, dividing workers at organic solvent exposed work place and workers of generalworkplace against which comparisons were carried out about the result of general characteristics, blood test.Whether exposed to organic solvent and exposed period relationship with metabolic syndrome components wereidentified through execution of multiple logistic regression analysis. The prevalence rate of the metabolic syndromeby age was 15.0% for the 30s, 19.8% for the 40s, 22.9% for the 50s. For the whole workers, the prevalence rateof the metabolic syndrome was 17.4% in exposed workplace and 18.4% in general workplace that was higherthan the rate in exposed workplace. Even if age, drinking, smoking, exercise, region and BMI were corrected,the exposure to the organic solvent was the higher the significance of blood pressure and fasting glucose werestatistically and also the longer the period of exposure was, the higher the significance of blood pressure wasstatistically. In this study, the exposure to the organic solvent showed a statistically significant relevance with bloodpressure and fasting glucose among the metabolic syndrome components and the period of exposure showed astatistically significant relevance with blood pressure. Further researches should be conducted by prospective cohortstudy about the organic solvent and the metabolic syndrome components supplementing the defects.
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